Endocrine Abstracts

Introduction: The androgen receptor (AR) as a steroid hormone receptor is crucial for the embryological male sex differentiation and the maintenance of the phenotypical male characteristics throughout life in addition to spermatogenesis. Mutations in the AR gene can disrupt its function leading to Androgen Insensitivity Syndrome (AIS). AIS has a recessive mode of inheritance and can be broadly classified into 3 phenotypical categories: complete androgen insensitivity syndrome ...

Introduction: Hyperosmolar Hyperglycemic State (HHS) is an uncommon and potentially fatal complication of diabetes. HHS is a medical emergency with high mortality. Therefore, it needs to be managed promptly and carefully utilising nationally agreed guidance. Delays in recognition and challenges in management may lead to poor outcome.Aim and Targets: The primary objective is to improve the recognition and management of HHS. The project was set to the stan...